We describe an epidemiological and clinical study of Clinical Anophthalmia in a population of consecutive live and stillborns enrolled in a hospital based registry of congenital malformations in Northeast Italy during the period from 1981 to 1989; 22 cases were detected among 368,256 births yielding a birth prevalence of 0.60 per 10,000 (95% CI 0.34-0.84); 20 cases were associated with at least one other major malformation.
Malformation syndrome, association, or sequence was diagnosed in 13, while a non-recognizable multiple defect pattern was observed in 7/20 (35%). A chromosomal anomaly was present in eight syndromic cases.
Mots-clés Pascal : Malformation, Oeil, Anophtalmie, Oeil pathologie, Congénital, Homme, Prévalence, Epidémiologie, Italie, Europe
Mots-clés Pascal anglais : Malformation, Eye, Anophthalmos, Eye disease, Congenital, Human, Prevalence, Epidemiology, Italy, Europe
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0195054
Code Inist : 002B09A. Création : 199406.