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  1. Laboratory profile of sickle cell disease : a cross-sectional analysis.

    Article - En anglais

    We have collected steady-state laboratory data for over 2600 patients, age 2 years and over, with sickle cell anemia (HbSS), HbSC disease, and HbS-bêta+-thalassemia.

    The packed cell volume (PCV) is lower in males than in females until 17 or 18 years of age in HbSS and ages 13 to 15 in HbSC, but then becomes consistently higher in males.

    After age 40, the PCV falls in HbSS.

    The steady-state leukocyte count in HbSS is higher than that in normals, blunting the utility of this measurement in the assessment of infection.

    Mots-clés Pascal : Anémie hématie falciforme, Thalassémie bêta, Hémopathie, Epidémiologie, Examen laboratoire, Numération, Hémogramme, Hématocrite, Fonction hépatique, Fonction rénale, Exploration clinique, Homme, Etats Unis, Amérique du Nord, Amérique

    Mots-clés Pascal anglais : Sickle cell anemia, bêta-Thalassemia, Hemopathy, Epidemiology, Laboratory investigations, Numeration, Blood cell count, Hematocrite, Liver function, Renal function, Clinical investigation, Human, United States, North America, America

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 93-0097163

    Code Inist : 002B19A01. Création : 199406.