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  1. Oxygen as a cause of blindness in premature infants : autopsy of a decade of errors in clinical epidemiologic research.

    Article - En anglais

    Several intellectual « autopsies » have recently reviewed errors in clinical epidemiologic studies of causation, such as the original claim that amyl nitrite « poppers » caused AIDS.

    The current autopsy was done to determine why it took more than a decade-1942 to 1954-to end an iatrogenic epidemic in which high-dose oxygen therapy led to retrolental fibroplasia (RLF) in premature infants, blinding about 10,000 of them.

    The autopsy revealed a museum of diverse intellectual pathology.

    When first noted, RLF was regarded as neither a new disease nor a postnatal effect.

    Mots-clés Pascal : Immunodéficit acquis syndrome, Virose, Infection, Epidémiologie, Fibroplasie rétrolentale, Autopsie, Prématuré, Oeil pathologie, Rétinopathie, Nourrisson, Homme, Réanimation, Nouveau né pathologie, Complication, Pathogénie, Anatomopathologie, Hypoxie, Etiologie

    Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Epidemiology, Retrolental fibroplasia, Autopsy, Premature, Eye disease, Retinopathy, Infant, Human, Resuscitation, Newborn diseases, Complication, Pathogenesis, Pathology, Hypoxia, Etiology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 93-0091882

    Code Inist : 002B09I. Création : 199406.