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  1. Should women with node-negative breast cancer receive adjuvant chemotherapy ? Insights from a decision analysis model.

    Article - En anglais

    The use of adjuvant chemotherapy in women with node-negative breast cancer has been controversial and actively debated since the 1988 National Cancer Institute Clinical Alert.

    We developed a decision analysis model that used the results of available randomized controlled trials to assess the potential clinical and financial effects of using adjuvant chemotherapy for groups of 45-year-old and 60-year-old women.

    Using the baseline assumptions, we found that chemotherapy increases quality adjusted life expectancy and survival by a substantial amount at a cost comparable to most accepted medical interventions.

    Mots-clés Pascal : Economie santé, Anticancéreux, Analyse coût efficacité, Recidive, Survie, Glande mammaire pathologie, Glande mammaire, Tumeur maligne, Homme, Femelle, Chimiothérapie, Prise décision, Arbre décision, Traitement adjuvant

    Mots-clés Pascal anglais : Health economy, Antineoplastic agent, Cost efficiency analysis, Relapse, Survival, Mammary gland diseases, Mammary gland, Malignant tumor, Human, Female, Chemotherapy, Decision making, Decision tree

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 93-0076355

    Code Inist : 002B02R02. Création : 199406.