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  1. Variance imputation for overviews of clinical trials with continuous response.

    Article - En anglais

    Overviews of clinical trials are an efficient and important means of summarizing information about a particular scientific area.

    When the outcome is a continuous variable, both treatment effect and variance estimates are required to construct a confidence interval for the overall treatment effect.

    Often, only partial information about the variance is provided in the publication of the clinical trial.

    This paper provides heuristic suggestions for variance imputation based on partial variance information.

    Both pretest-posttest (parallel groups) and crossover designs are considered.

    Mots-clés Pascal : Métaanalyse, Essai clinique, Méthode statistique, Méthodologie

    Mots-clés Pascal anglais : Metaanalysis, Clinical trial, Statistical method, Methodology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 92-0420147

    Code Inist : 002B28F. Création : 199406.