A large-scale study of genetic influences on seizure disorders is described here as a primer of tested methods for collection of family history data. 1957 adult probands with epilepsy were ascertained from voluntary organizations.
Personal and family history data were obtained from probands in semistructured telephone interviews.
To increase sensitivity, an independent family history was obtained from a second family informant in a similar interview.
To increase specificity and diagnostic detail, family members reported to be affected were interviewed, and medical records of probands and affected relatives were collected.
Mots-clés Pascal : Epilepsie, Système nerveux pathologie, Convulsion, Epidémiologie, Déterminisme génétique, Etude familiale, Méthodologie, Collecte donnée, Entretien, Homme, Etats Unis, Amérique du Nord, Amérique
Mots-clés Pascal anglais : Epilepsy, Nervous system diseases, Convulsion, Epidemiology, Inheritance, Family study, Methodology, Data gathering, Interview, Human, United States, North America, America
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 92-0420142
Code Inist : 002B17A03. Création : 199406.