Long-term behavior of naturally acquired anti-HBs antibody was tested every 6 months (or 3 years in 22 dialysis patients.
Fifteen of them maintained protective levels throughout follow-up (102 and 85.5 mUI/ml at the beginning and the end, respectively).
Seven of them become anti-HBs and were submitted to a 40-mug booster injection of hepatitis B vaccine.
Seroconversion was observed in 6 of 7 patients (85.7%) with a mean anti-HBs titer of 90.4 and 47.3 mUI/ml after 3 and 6 months, respectively.
Protective anti-HBs level may be maintained longer in patients with natural immunity than in HBsAg-negative vaccinated subjects.
Mots-clés Pascal : Hémodialyse, Epuration extrarénale, Réanimation, Appareil urinaire pathologie, Homme, Anticorps, Virus hépatite B, Hepadnaviridae, Virus, Concentration, Indication, Vaccination, Immunisation, Epidémiologie
Mots-clés Pascal anglais : Hemodialysis, Extrarenal dialysis, Resuscitation, Urinary system disease, Human, Antibody, Hepatitis B virus, Hepadnaviridae, Virus, Concentration, Indication, Vaccination, Immunization, Epidemiology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 92-0392077
Code Inist : 002B27B03. Création : 199406.