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  1. PCR amplification of alleles at the DIS80 locus : comparison of a finnish and a North American caucasian population sample, and forensic caework evaluation.

    Article - En anglais

    Allele and genotype frequencies for the highly polymorphic D1S80 locus were determined in a Finnish population sample by using PCR followed by high-resolution PAGE and silver staining, a procedure called the amplified-fragment-length polymorphism (Amp-FLP) technique.

    In 140 unrelated Finnish individuals 1 5 alleles and 43 phenotypes were observed.

    The D1S80 locus demonstrated a heterozygosity of.77, and the power of discrimination was.92 in this sample representing a genetically isolated Finnish population.

    The distribution of observed genotypes conformed to Hardy-Weinberg expectations.

    Mots-clés Pascal : Séquence répétée en tandem, Génétique population, Finlande, Europe, Polymorphisme longueur fragment restriction, Biologie moléculaire, Génétique, Amplification, Méthode, Réaction chaîne polymérase, Génotype, Allèle, Fréquence, Aspect médicolégal, Homme, D1S80 locus

    Mots-clés Pascal anglais : Tandemly repeated sequence, Population genetics, Finland, Europe, Restriction fragment length polymorphism, Molecular biology, Genetics, Amplification, Method, Polymerase chain reaction, Genotype, Allele, Frequency, Forensic aspect, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 92-0356107

    Code Inist : 002A07C03. Création : 199406.