Favism is a potentially fatal manifestation of glucose-6-phosphate dehydrogenase (G6PD) deficiency, and it is therefore a public gealth problem in areas where this genetic abnormality is common.
In the district or Sassari (northern Sardinia), the frequency of G6PD male hemizygotes is approximately 7.5%, and therefore all newborns since 1971 have been screened for G6PD deficiency.
We have analyzed the incidence of favism in this community in two 10 year periods: (1) 1961-1970; and (2) 1981-1990.
In period (1) there were 508 cases of favism, of which 76% occured in boys.
Mots-clés Pascal : Déficit, Glucose-6-phosphate dehydrogenase, Enzyme, Dépistage, Incidence, Favisme, Education sanitaire, Sardaigne, Italie, Europe, Nord, Epidémiologie, Hémopathie, Enzymopathie, Maladie héréditaire, Nouveau né, Homme
Mots-clés Pascal anglais : Deficiency, Glucose-6-phosphate dehydrogenase, Enzyme, Medical screening, Incidence, Favism, Health education, Sardinia, Italy, Europe, North, Epidemiology, Hemopathy, Enzymopathy, Genetic disease, Newborn, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 92-0339417
Code Inist : 002B19A01. Création : 199406.