High-level resistance to gentamicin in Enterococcus faecium.
During a six-month period in a hospital in Ireland, four patients were infected (isolation from blood cultures) and two were colonized (isolation from rectal swabs) with strains of Enterococcus faecium highly resistant to gentamicin.
MICs of gentamicin were >1000 mg/L for all six strains, and each possessed a plasmid of approximntely 50 MDa.
Resistance to gentamicin was transferable by conjugation from two of the six strains, and was associated with transfer of the 50 M Da plasmid.
Mots-clés Pascal : Gentamicine, Résistance, Enterococcus faecium, Streptococcaceae, Micrococcales, Bactérie, Mécanisme, Plasmide, Enzyme, Prélèvement, Homme, Hôpital, Irlande, Europe, Antibiotique, Antibactérien, Aminoglycoside
Mots-clés Pascal anglais : Resistance, Enterococcus faecium, Streptococcaceae, Micrococcales, Bacteria, Mechanism, Plasmid, Enzyme, Samplings, Human, Hospital, Ireland, Europe, Antibiotic, Antibacterial agent, Aminoglycoside
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 92-0338558
Code Inist : 002B02S02. Création : 199406.