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  1. Inducible processes in human cells by low doses of genotoxic physical and chemical factors.

    Article - En anglais

    We are continuously exposed to low levels of genotoxic agents from our indoor and outdoor environment.

    Human cells have different responses to continuous DNA damage, depending on the DNA repair capacity and related factors.

    Exposure to very low levels of alkylating agents for one or two cell cycles renders the cells more resistant due to the induction of DNA methyltransferase.

    Exposure of NOx can lead to formation of N-nitroso compounds in the human body which may act in a similar way.

    Mots-clés Pascal : Pollution intérieur, Toxicité, Homme, Carcinogène, Mutagène, DNA, Concentration maximale admissible, Pollution air, Autriche, Europe, Adaptation, Réparation, Défense organisme, Dose faible, Methylated-DNA-protein-cysteine methyltransferase, Enzyme, NAD+ ADP-ribosyltransferase

    Mots-clés Pascal anglais : Indoor pollution, Toxicity, Human, Carcinogen, Mutagen, DNA, Maximum permissible concentration, Air pollution, Austria, Europe, Adaptation, Repair, Defense, Low dose, Methylated-DNA-protein-cysteine methyltransferase, Enzyme, NAD+ ADP-ribosyltransferase

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 92-0309400

    Code Inist : 002B03M02. Création : 199406.