A cohort of 917 Down syndrome (DS) children born in Italy between 1978 and 1984 was studied for survival through the age of 8 years.
The highest mortality occurred in the first month of life (7.9%); survival was about 80% at 1 year, 78% at 2 years, and 76% at 5 years, with small decreases thereafter.
At the univariate analysis, survival was lower for subjects with congenital heart disease (CHD), birth weight <2,500 g, parity of 3 or plus, maternal age >=35 years, and for those born in Southern Italy compared with Northern Italy.
Mots-clés Pascal : Trisomie, Aneuploïdie, Aberration chromosomique, Chromosome G21, Enfant, Homme, Survie, Italie, Europe, Epidémiologie
Mots-clés Pascal anglais : Trisomy, Aneuploidy, Chromosomal aberration, G21-Chromosome, Child, Human, Survival, Italy, Europe, Epidemiology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 92-0236362
Code Inist : 002B23B. Création : 199406.