Conference on antioxidant vitamins and B-carotene in disease prevention. London (GBR), 1989/10/02.
Cancer chemoprevention research takes leads from epidemiologic and laboratory research and develops them through in vitro and in vivo preclinical research and initial human studies into randomized controlled trials.
At present, the chemoprevention program is sponsoring 21 human efficacy studies.
These trials are testing the potential of agents (bêta-carotene, folic acid, 13-cis retinoic acid, 4-hydroxyphenyl retinamide, vitamins C and E, and minerals) as inhibitors of a variety of cancers in humans (colon, lung, esophagus, cervix, bladder, and skin).
Endpoints in these studies include overall incidence of cancer, incidence of specific cancers, rate of regression or progression of preneoplastic changes, and changes in cellular or biochemical parameters.
Mots-clés Pascal : Homme, Animal, Tumeur, Tumeur maligne, Prévention, Epidémiologie, Antioxydant, Tocophérol, Ascorbique acide, bêta-Carotène
Mots-clés Pascal anglais : Human, Animal, Tumor, Malignant tumor, Prevention, Epidemiology, Antioxidant, Tocopherol, Ascorbic acid
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 92-0638033
Code Inist : 002B04. Création : 199406.