Conference on antioxidant vitamins and B-carotene in disease prevention. London (GBR), 1989/10/02.
In 1971-1973 at the third examination of the Basel Study in 1959, the major antioxidant vitamins and carotene were measured in the plasma of 2974 men.
A subsample and their families were reinvestigated in 1977-79.
During the 12-y observation period (1973-85) 553 men died, 204 of cancer (lung cancer 68, stomach cancer 20; colon cancer 17, all other malignancies 99).
We found significantly lower mean carotene levels for all cancer, bronchus cancer, and stomach cancer (all P<0.01) compared with 2421 survivors.
The relative risk of subjects with low carotene (<0.23 mumol/L) was significantly elevated (P<0.05) for lung cancer (Cox's model).
Higher risks were noted for all cancer (P<0.01) if both carotene and retinol were low.
Mots-clés Pascal : Homme, Tumeur, Tumeur maligne, Prévention, Epidémiologie, Rétinol, bêta-Carotène
Mots-clés Pascal anglais : Human, Tumor, Malignant tumor, Prevention, Epidemiology, Retinol
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 92-0638027
Code Inist : 002B04. Création : 199406.