Prediagnostic serum levels of carotenoids and vitamin E as related to subsequent cancer in Washington county, Maryland.
Conference on antioxidant vitamins and B-carotene in disease prevention. London (GBR), 1989/10/02.
In 1974 and 1975, serum specimens were collected from 25802 volunteers in Washington County, Maryland.
The serum was kept frozen at -73°C until the time os assay.
Prediagnostic samples from 436 cancer cases and 765 matched control subjects have been assayed.
Nine sites have been studied: colon, rectum, pancreas, lung, melanoma, basal cell of skin, breast, prostate, and bladder.
Serum bêta-carotene levels showed a strong protective association with lung cancer, suggestive protective associations with melanoma and bladder cancer, and a suggestive but nonprotective association with rectal cancer.
Serum vitamin E levels had a protective association with lung cancer: none of the other sites showed impressive associations.
Mots-clés Pascal : Homme, Tumeur, Tumeur maligne, Epidémiologie, Prévention, Tocophérol, Caroténoïde, Lycopène
Mots-clés Pascal anglais : Human, Tumor, Malignant tumor, Epidemiology, Prevention, Tocopherol
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 92-0638026
Code Inist : 002B04. Création : 199406.