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  1. DNA instability, paternal irradiation and leukaemia in children around sellafield.

    Article - En anglais

    The chemical instability of DNA under physiological conditions requires that cells have highly developed processes for repairing stochastic single-strand damage.

    It is proposed here that provided ionizing-radiation-induced single-strand damage does not occur at a rate sufficient to perturb the dynamic steadystate between degradation and repair, it can be regarded as 'irrelevant' to biological effect, leaving double-strand damage and DNA-protein crosslinks as 'relevant' damage to biological effect.

    Mots-clés Pascal : Radiocontamination, Irradiation ionisante, Risque, Leucémie, Hémopathie maligne, Père, Lignée germinale, Radiolésion, DNA, Spermatogenèse, Mutation, Radiobiologie, Biophysique, Sellafield

    Mots-clés Pascal anglais : Radioactive contamination, Ionizing irradiation, Risk, Leukemia, Malignant hemopathy, Father, Germ line, Radiation injury, DNA, Spermatogenesis, Mutation, Radiobiology, Biophysics

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 92-0245471

    Code Inist : 002A08F03. Création : 199406.