The objective of this study was to investigate household clustering of hepatitis B virus (HBV) infection in South Africa in order to understand intra-household patterns of virus transmission that would provide information on potential risk factors of HBV infection.
Subjects were the household contacts of 28 hepatitis B surface antigen (HBsAg) positive children (index-carrier), 22 hepatitis B surface antibody positive children (index-past-infection) and 35 children with no serological evidence of HBV infection (index-negative).
Evidence of HBV infection (at least one positive HBV marker) was present in 73.7%, 48.7% and 38.2% and HBsAg was present in 19.9%, 8.7% and 2.9% of household contacts of index-carrier (N=186), index-past-infection (N=150) and index-negative (N=207) children respectively.
Mots-clés Pascal : Virose, Infection, Homme, Afrique, Hépatite virale B, Transmission homme homme, Dissémination, Enfant, Epidémiologie, Sérologie, Milieu familial, Foie pathologie, Appareil digestif pathologie, République Sud Africaine
Mots-clés Pascal anglais : Viral disease, Infection, Human, Africa, Viral hepatitis B, Transmission from man to man, Dissemination, Child, Epidemiology, Serology, Family environment, Hepatic disease, Digestive diseases, South Africa
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 91-0586696
Code Inist : 002B05C02G. Création : 199406.