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  1. Pneumococcal vaccine trials in Papua New Guinea : relationships between epidemiology of pneumococcal infection and efficacy of vaccine.

    Article, Congrès - En anglais

    Onference on the pathogenesis and prevention of pneumonia in children in developing regions. Bellagio (ITA), 1989-08-21.

    Field trials in Papua New Guinea have shown that pneumococcal capsular polysaccharide vaccine protects children <2 years of age from death due to acute lower respiratory infections (ALRI).

    The vaccine appears to reduce mortality by preventing bacteremia.

    Evidence suggests that highly invasive « adult » pneumococcal serotypes are comparatively more important as a cause of ALRI in developing countries where ALRI-related mortality is higher than in North America.

    Capsular polysaccharide vaccines are more likely to be immunogenic for these serotypes than for the « pediatric » serotypes.

    Mots-clés Pascal : Infection, Streptococcaceae, Micrococcales, Bactérie, Mélanésie, Océanie, Homme, Bactériose, Appareil respiratoire, Streptococcus pneumoniae, Epidémiologie, Vaccin, Vaccination, Efficacité, Papouasie Nouvelle Guinée, Appareil respiratoire pathologie, Enfant

    Mots-clés Pascal anglais : Infection, Streptococcaceae, Micrococcales, Bacteria, Melanesia, Oceania, Human, Bacteriosis, Respiratory system, Streptococcus pneumoniae, Epidemiology, Vaccine, Vaccination, Efficiency, Papua New Guinea, Respiratory disease, Child

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 91-0586260

    Code Inist : 002B05B02E. Création : 199406.