Experimental evidence suggests that folate depletion plays a role in carcinogenesis.
A case-control study examining folate intake was conducted.
Some 428 colon and 372 rectal cancer cases with matched neighbourhood controls were interviewed regarding usual intake of foods, including food preparation.
Unadjusted folate was not associated with risk of either cancer.
Controlling for kilocalories, odds ratios (ORs) for those with the highest folate intake were 0.5 (95% confidence interval (Cl): 0,24-1.03) and 0.31 (95% Cl:0.16-0.59) for females and males for rectal cancer.
There was no change in colon cancer risk associated with folate intake.
Mots-clés Pascal : Etats Unis, Amérique du Nord, Amérique, Tumeur, Côlon, Rectum, Epidémiologie, Homme, Consommation alimentaire, Folique acide, Facteur risque, Comportement alimentaire, Tumeur maligne, Appareil digestif pathologie, New York
Mots-clés Pascal anglais : United States, North America, America, Tumor, Colon, Rectum, Epidemiology, Human, Food intake, Folic acid, Risk factor, Feeding behavior, Malignant tumor, Digestive diseases, New York
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 91-0580782
Code Inist : 002B13B01. Création : 199406.