Reporting errors in time-to-pregnancy data collected with a short questionnaire : impact on power and estimation of fecundability ratios.
In a study of occupational exposures to dental assistants conducted in 1987-1988, 523 women provided time-to-pregnancy data both on a short, mailed questionnaire and in a detailed telephone interview.
The correlation between the two measures was 0.82.
Assuming that the detailed data were accurate, reporting errors in data from the short form were distributed nondifferentially with respect to most covariates of interest in fecundability analyses.
Simulation studies were conducted to estimate bias and loss of power from the misclassification.
Bias was toward the null.
Substantial power was lost in detecting weak exposures.
However, exposures that reduce fecundability by 50 percent (equivalent to adding about three cycles to the median time to pregnancy) could still be detected with 80 percent power in samples of about 100 women.
(half of them exposed to a possible toxin).
Mots-clés Pascal : Etats Unis, Amérique du Nord, Amérique, Stérilité, Questionnaire, Entretien, Etude comparative, Biais méthodologique, Méthodologie, Homme, Epidémiologie, Autoévaluation, Exposition professionnelle, Californie
Mots-clés Pascal anglais : United States, North America, America, Sterility, Questionnaire, Interview, Comparative study, Methodological bias, Methodology, Human, Epidemiology, Self evaluation, Occupational exposure, California
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 91-0569830
Code Inist : 002B20A04. Création : 199406.