Serum specimens obtained from a nationwide sample of parenteral drug abusers (PDAs) during the period 1971-72 had previously been screened for human immunodeficiency virus (HIV) antibodies.
Some specimens were considered to be positive to both ELISA and Western blot (WB) analysis.
These findings have been a topic of controversy, since HIV was not thought to have penetrated at-risk populations at such an early date.
This study was a followup of those PDAs with apparent seropositivity to WB analysis.
We concluded that the earlier WB results were most likely false positives and that definitive evidence of HIV infection in the U.S. addict populations as early as 1971-72 is still lacking.
Mots-clés Pascal : Virose, Infection, Amérique du Nord, Amérique, Immunodéficit acquis syndrome, Séropositivité, Faux positif, Sérologie, Technique ELISA, Méthode immunoblotting, Dépistage, Toxicomanie, Voie parentérale, Etude longitudinale, Immunopathologie, Hémopathie, Homme, Etats Unis
Mots-clés Pascal anglais : Viral disease, Infection, North America, America, AIDS, Seropositivity, False positive, Serology, ELISA assay, Immunoblotting assay, Screening, Drug abuse, Parenteral administration, Follow up study, Immunopathology, Hemopathy, Human, United States
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 91-0560106
Code Inist : 002B06D01. Création : 199406.