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  1. Association with prior fluoroquinolone therapy of widespread ciprofloxacin resistance among Gram-negative isolates in a Veterans Affairs Medical Center.

    Article - En anglais

    We performed a case-control study of risk factors for the acquisition of ciprofloxacin-resistant- gram-negative isolates in a Veterans Affairs medical center.

    Sixty-five patients with resistant isolates and 50 control patientswere identified.

    Prior fluoroquinolone use was significantly more fraquent among patients with isolates than it was among controls (58 versus 20%; p=0.0001).

    The association with prior quinolone use was stronger in the long-term-care division (81 versus 32%; p=0.0005) than it was in the acute-care division (29 versus 0%; p=0.015).

    On multivariate analysis, rior receipt of a fluoroquinolone was the single most significant risk factor for isolation of a ciprofloxacin-resistant gram-negative organism(p=0.0001).

    Mots-clés Pascal : Infection, Ancien combattant, Facteur risque, Bactériose, Bactérie Gram négatif, Homme, Résistance, Ciprofloxacine, Antibactérien, Isolat clinique, Epidémiologie, Fluoroquinolone dérivé

    Mots-clés Pascal anglais : Infection, Veteran, Risk factor, Bacteriosis, Gram negative bacteria, Human, Resistance, Antibacterial agent, Clinical isolate, Epidemiology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 91-0360016

    Code Inist : 002B02S02. Création : 199406.