Familial cases of non-polyposis colorectal cancer have attracted much interest but little is known of their natural history.
Using a population based study we have determined whether a positive family history of bowel cancer is an independent prognostic factor.
All patients under 55 years with histologically confirmed colorectal cancer in Northern Ireland during the period 1976-8 were studied.
The family history was validated in 95% of all non-polyposis cases (n=205).
Medical history or cause of death were veiled for 98% of 1811 first degree relatives.
Mots-clés Pascal : Royaume Uni, Europe, Tumeur, Tumeur maligne, Côlon, Rectum, Maladie héréditaire, Etude familiale, Pronostic, Facteur risque, Ulster, Epidémiologie, Intestin pathologie, Appareil digestif pathologie, Homme, Adulte
Mots-clés Pascal anglais : United Kingdom, Europe, Tumor, Malignant tumor, Colon, Rectum, Genetic disease, Family study, Prognosis, Risk factor, Northern Ireland, Epidemiology, Intestinal disease, Digestive diseases, Human, Adult
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 91-0359850
Code Inist : 002B13B01. Création : 199406.