Based on an established but pragmatic definition of cancer family syndrome as the presence of three or more relatives affected by colorectal cancer in a first degree kinship, the contribution of this syndrome to the total cancer burden in Northern Ireland has been studied by investigating all non-polyposis probands under 55 years old at histological diagnosis between 1976 and 1978.
Family interviews were possible for 95% (n=205) of all non-polyposis probands and verification of vital status or medical history was obtained for 98% of 1811 first degree relatives.
Mots-clés Pascal : Royaume Uni, Europe, Tumeur, Tumeur maligne, Côlon, Rectum, Maladie héréditaire, Ulster, Etude familiale, Prévalence, Epidémiologie, Intestin pathologie, Appareil digestif pathologie, Homme, Adulte jeune
Mots-clés Pascal anglais : United Kingdom, Europe, Tumor, Malignant tumor, Colon, Rectum, Genetic disease, Northern Ireland, Family study, Prevalence, Epidemiology, Intestinal disease, Digestive diseases, Human, Young adult
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 91-0359849
Code Inist : 002B13B01. Création : 199406.