Systemic cancer and the FAMMM syndrome.
We have studied cancer of all anatomic sites and histologies in nine FAMMM families which were ascertained in a pigmented lesions clinic in the Netherlands.
We evaluated two hypotheses; that the number of systemic cancers observed in the families was excessive, compared to expected incidence, based on Dutch incidence data, and that there was variation (or heterogeneity) among families in the frequency of systemic cancer.
Mots-clés Pascal : Tumeur, Peau, Mélanome malin, Multiple, Naevus, Association, Dysplasie, Généralisé, Incidence, Complication, Etude familiale, Epidémiologie, Tumeur maligne, Maladie héréditaire, Peau pathologie, Homme
Mots-clés Pascal anglais : Tumor, Skin, Malignant melanoma, Multiple, Nevus, Association, Dysplasia, Systemic, Incidence, Complication, Family study, Epidemiology, Malignant tumor, Genetic disease, Skin disease, Human
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 91-0331264
Code Inist : 002B08A. Création : 199406.