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  1. Multidrug therapy for treatment of paucibacillary leprosy in Western Kenya : preliminary communications.

    Article - En anglais

    A prospective study is being undertaken in Western Kenya to evaluate the effectiveness and tolerability of WHo-MDT, while at the same time comparing it to a modified multidrug regimen, which is rifampicin 1500mg at the onset supervised, and repeated after 3 months and dapsone 100mg daily for 6 months.

    Preliminary analysis done on 127 cases admitted into the study are presented.

    The inactivity index observed between 0-12 weeks was 20% for WHO-MDT and 47% for modified-MDT (p<0.01).

    The inactivity index observed between 0-24 weeks was 63.3% for WHO-MDT and 82.3% for modified-MDT (p<0.05).

    The inactivity index observed between 0-32 weeks was 83% for WHO-MDT, and 88% for modified-MDT.

    Mots-clés Pascal : Mycobactériose, Bactériose, Infection, Afrique, Lèpre, Kenya, Plan traitement, OMS, Antibiotique, Peau pathologie, Homme

    Mots-clés Pascal anglais : Mycobacterial infection, Bacteriosis, Infection, Africa, Leprosy, Kenya, Treatment planning, WHO, Antibiotic, Skin disease, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 91-0210091

    Code Inist : 002B02S02. Création : 199406.