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  1. Genetic epidemiology of bilateral breast cancer: a linkage analysis using the affected-pedigree-member method.

    Article - En anglais

    We used the affected-pedigree-member (APM) method to conduct linkage analyses on 19 pedigrees in which the probands had premenopausal bilateral breast cancer.

    This method analyzes all affected pairs of relatives, as opposed to siblings only, and incorporates into the analyses information on the frequency of marker alleles.

    Fourteen codominant marker systems were evaluated in two separate analyses.

    Mots-clés Pascal : Génétique épidémiologique, Glande mammaire, Bilatéral, Tumeur, Glande mammaire pathologie, Epidémiologie, Homme, Etude familiale, Marqueur génétique, Biologie moléculaire, Génétique, Linkage

    Mots-clés Pascal anglais : Epidemiologic genetics, Mammary gland, Bilateral, Tumor, Mammary gland diseases, Epidemiology, Human, Family study, Genetic marker, Molecular biology, Genetics, Linkage

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 91-0183539

    Code Inist : 002B20E02. Création : 199406.