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  1. Malignant tumors during the first 2 decades of life in the offspring of atomic bomb survivors.

    Article - En anglais

    The risk of cancer (incidence) prior to age 20 years has been determined for children born to atomic bomb survivors and to a suitable comparison group.

    Tumor ascertainment was through death certificates and the tumor registries maintained in Hiroshima and Nagasaki.

    The rationale for the study stemmed from the evidence that a significant proportion of such childhood tumors as retinoblastoma and Wilms tumor arise on the basis of a mutant gene inherited from one parent plus a second somatic cell mutation involving the allele of this gene.

    Mots-clés Pascal : Asie, Homme, Irradiation ionisante, Japon, Incidence, Radiocontamination, Dose rayonnement, Biophysique, Radiobiologie, Mutation, Tumeur maligne, Epidémiologie, Facteur risque, Nourrisson, Cellule somatique, Etude familiale, Gène, Bombe atomique

    Mots-clés Pascal anglais : Asia, Human, Ionizing irradiation, Japan, Incidence, Radioactive contamination, Radiation dose, Biophysics, Radiobiology, Mutation, Malignant tumor, Epidemiology, Risk factor, Infant, Somatic cell, Family study, Gene

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 91-0074392

    Code Inist : 002A08F02. Création : 199406.