Cardiovascular risk factors in a french Canadian population: resolution of genetic and familial environmental effects on blood pressure using twins, adoptees, and extensive information on environmental correlates.
Genetic and environmental influences on systolic (SBP), diastolic (DBP), and mean arterial (MBP) blood pressure were examined using an expanded version of a path model in which parents and their singleton, twin, and adopted offspring were incorporated, and which also included an environmental index as an estimate of the underlying familial environmental component.
Estimates of genetic heritability are lower in parents (10-15%) than in offspring (40-50%).
Mots-clés Pascal : Pression sanguine, Environnement, Canadien français, Héritabilité, Déterminisme génétique, Epidémiologie, Homme, Etude familiale, Etude statistique
Mots-clés Pascal anglais : Blood pressure, Environment, French canadian, Heritability, Inheritance, Epidemiology, Human, Family study, Statistical study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 91-0189012
Code Inist : 002A07C03. Création : 199406.