Numerous studies have observed that workers in ferriferous industries have an elevated risk of respiratory tract neoplasia Research at the cellular and animal model levels indicates that iron compounds, per se, are carcinogenic.
However, some investigators have suggested that inhaled iron compounds are merely carriers of other carcinogens.
Evidence is presented that iron apparently is a principal carcinogenic hazard in inhalation of silicon dioxide, asbestos, and tobacco smoke.
Included in the discussion are unresolved questions concerning the precise role of inhaled iron as a carcinogen.
Mots-clés Pascal : Tumeur maligne, Bronchopulmonaire, Carcinogène, Fer, Exposition professionnelle, Tabagisme, Amiante, Inhalation, Métal, Elément minéral, Carcinogenèse, Homme, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie, Médecine travail
Mots-clés Pascal anglais : Malignant tumor, Bronchopulmonary, Carcinogen, Iron, Occupational exposure, Tobacco smoking, Asbestos, Inhalation, Metal, Inorganic element, Carcinogenesis, Human, Respiratory disease, Lung disease, Bronchus disease, Occupational medicine
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0519552
Code Inist : 002B03L05. Création : 18/05/2000.