To investigate the mechanism of gastric motility suppression by exposure to whole-body vibration (WBV).
The gastric motility was evaluated by electrogastrography (EGG) under food intake and autonomic nerve blocking agents in ten healthy volunteers.
Sinusoidal vertical vibration with a frequency of 4 Hz (1.0 ms-2 rms) was given to the subject for 10 min.
The amplitude of EGG wave and the power spectrum corresponding to the slow wave component was remarkably decreased by vibration exposure.
Food intake enhanced the gastric motility about 2.5-fold in the power spectral density.
During and after vibration exposure, the response mode was similar to those at fasting states.
Under the influence of anticholinergic (scopolamine) and alpha-adrenergic blocking agents (prazosin), the power spectra were decreased.
A further decrease was observed during vibration exposure.
A beta-adrenergic blocking agent (propranolol) led to a marked increase in the amplitude of EGG and its power spectrum.
With pretreatment by a beta-adrenergic blocking agent, however, vibration exposure reduced both of them.
These results suggest that short-term exposure to WBV can suppress the gastric myoelectric activity, the responses on which may be mediating by neurohumoral effects as well as the mechanical effect of WBV.
Mots-clés Pascal : Trouble dû aux vibrations, Exposition professionnelle, Médecine travail, Homme, Motilité, Estomac, Consommation alimentaire, Appareil digestif pathologie, Electrogastrographie
Mots-clés Pascal anglais : Vibration induced disorder, Occupational exposure, Occupational medicine, Human, Motility, Stomach, Food intake, Digestive diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0519500
Code Inist : 002B13B03. Création : 18/05/2000.