A case is presented involving an acute fatality resulting from self-administered alpha-chloralose, a rodenticide.
A 18-year-old man was found dead at home, with several stains of vomit on the carpet.
An empty box of three bags of 5 g 100% alpha-chloralose (Corbeaux nuisibles, Rhône Poulenc) was found near the body.
The compound was identified and quantified by headspace gas chromatography coupled to mass spectrometry.
Alpha-chloralose was converted by concentrated sulphuric acid into chloral, a volatile compound, that was, after chromatography on a HP5-MS capillary column, identified by the following ions, m/z 82,111 and 148.
Peripheral blood concentration was 175.7 mg/l, Alpha-chloralose was quantified in several tissues, indicating kidney sequestration.
No other drugs, including ethanol, were detected.
Mots-clés Pascal : Etude cas, Chloralose, Toxique, Intoxication, Postmortem, Suicide, Spectrométrie masse, Exploration toxicologique, Homme, Mâle, Glucochloral, Alpha-chloralose
Mots-clés Pascal anglais : Case study, Chloralose, Poison, Poisoning, Postmortem, Suicide, Mass spectrometry, Toxicological exploration, Human, Male
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0517994
Code Inist : 002B30A10. Création : 18/05/2000.