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  1. Testing for alpha-chloralose by headspace-GC/MS : A case report.

    Article - En anglais

    A case is presented involving an acute fatality resulting from self-administered alpha-chloralose, a rodenticide.

    A 18-year-old man was found dead at home, with several stains of vomit on the carpet.

    An empty box of three bags of 5 g 100% alpha-chloralose (Corbeaux nuisibles, Rhône Poulenc) was found near the body.

    The compound was identified and quantified by headspace gas chromatography coupled to mass spectrometry.

    Alpha-chloralose was converted by concentrated sulphuric acid into chloral, a volatile compound, that was, after chromatography on a HP5-MS capillary column, identified by the following ions, m/z 82,111 and 148.

    Peripheral blood concentration was 175.7 mg/l, Alpha-chloralose was quantified in several tissues, indicating kidney sequestration.

    No other drugs, including ethanol, were detected.

    Mots-clés Pascal : Etude cas, Chloralose, Toxique, Intoxication, Postmortem, Suicide, Spectrométrie masse, Exploration toxicologique, Homme, Mâle, Glucochloral, Alpha-chloralose

    Mots-clés Pascal anglais : Case study, Chloralose, Poison, Poisoning, Postmortem, Suicide, Mass spectrometry, Toxicological exploration, Human, Male

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0517994

    Code Inist : 002B30A10. Création : 18/05/2000.