Analysis of incidence of childhood cancer in the West Midlands of the United Kingdom in relation to proximity to main roads and petrol stations.
Objectives-To investigate whether there is an excess of leukaemias in 0-15 year old children among those living in close proximity (within 100 m) of a main road or petrol station.
Methods-Data for 0-15 year old children diagnosed between 1990 and 1994 in the United Kingdom West Midlands were used.
Postcode addresses were used to locate the point of residence which was compared with proximity to main roads and petrol stations separately, and to both together.
Odds ratios (ORs) were calculated with solid tumours as a control, and incidence ratios (IRs) with population density as a control.
The method based on solid tumours as a control showed ORs of 1.61 (95% confidence interval (95% CI) 0.90 to 2.87) and 1.99 (95% CI 0.73 to 5.43), for those living within 100 m ofa main road or petrol station respectively.
When population was used as a control, the estimated IRs for leukaemia were 1.16 (95% CI 0.74 to 1.72) and 1.48 (95% CI 0.65 to 2.93) for residence within 100 m of a main road or petrol station respectively, but neither reached significance at the 95% level.
Results for residence in close proximity to both a main road and petrol station were inconsistent, but there were few.
The influence of socioeconomic factors as represented by the Townsend deprivation index on leukaemia incidence was not significant and the results were not explicable on the basis of impact of social class. (...)
Mots-clés Pascal : Enfant, Homme, Tumeur maligne, Epidémiologie, Royaume Uni, Europe, Pollution, Environnement, Leucémie, Trafic routier, Proximité, Zone résidentielle, Zone industrielle, Industrie pétrolière, Santé et environnement, Hémopathie maligne
Mots-clés Pascal anglais : Child, Human, Malignant tumor, Epidemiology, United Kingdom, Europe, Pollution, Environment, Leukemia, Road traffic, Proximity, Residential zone, Industrial area, Oil industry, Health and environment, Malignant hemopathy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0508102
Code Inist : 002B04B. Création : 22/03/2000.