To investigate the risk of gastric cancer associated with 12 workplace exposures suspected or discussed as aetiological agents in previous reports.
Methods-A case-control study was conducted based on the death certificates of several million deaths in 24 states of the United States in 1984-96.
Overall, the data base included 41 957 deaths from stomach cancer among subjects aged >=25 years.
These were 20 878 white men, 14 125 white women, 4215 African American men, and 2739 African American women.
Two controls for each case were selected from among subjects who died from non-malignant diseases, frequency matched to cases by geographic region, race, sex and 5 year age group.
Each three digit occupation and industry code listed in the 1980 United States census was classified for probability and intensity of exposure to asbestos, inorganic dust, metals, lead, polycyclic aromatic hydrocarbons (PAHs), nitrogen oxides, nitrosamines, sulphuric acid, fertilisers, herbicides, other pesticides (including insecticides and fungicides), and wood dust.
These job exposure matrices were subsequently applied to the occupation-industry combinations in the death certificates of study subjects, separately by sex and race.
Risk of stomach cancer showed a modest association with occupational exposure to inorganic dust (odds ratio (OR)=1.06 ; 95% confidence interval (95% CI) 1.03 to 1. (...)
Mots-clés Pascal : Lieu travail, Exposition professionnelle, Médecine travail, Tumeur maligne, Estomac, Facteur risque, Epidémiologie, Certificat décès, Homme, Etats Unis, Amérique du Nord, Amérique, Etiologie, Appareil digestif pathologie, Estomac pathologie, Matrice emploi exposition
Mots-clés Pascal anglais : Work place, Occupational exposure, Occupational medicine, Malignant tumor, Stomach, Risk factor, Epidemiology, Death certificate, Human, United States, North America, America, Etiology, Digestive diseases, Gastric disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0507017
Code Inist : 002B13B01. Création : 22/03/2000.