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  1. Fulltext. Cardiovascular risk factors clustering features of insulin resistance syndrome (Syndrome X) in a biracial (Black-White) population of children, adolescents, and young adults : The Bogalusa Heart Study.

    Article - En anglais


    Recently, independent factors representing different features of insulin resistance syndrome (Syndrome X) have been identified by factor analysis in middle-aged and elderly adult populations.

    In this study, factor analysis was applied to the clustering characteristics of Syndrome X in a biracial (Black-White) community-based population of 4,522 children (ages 5-11 years), adolescents (ages 12-17 years), and young adults (ages 18-38 years) from the Bogalusa Heart Study who were screened during 1988-1996.

    Ponderal index (weight (kg)/height (m) 3), levels of insulin, glucose, triglycerides, and high density lipoprotein cholesterol, and systolic and diastolic blood pressure were used as measures of components of Syndrome X. No evidence was found to support a one-factor hypothesis for this syndrome, but factor analysis yielded two uncorrelated factors (factor 1 : insulin/lipids/glucose/ponderal index ; factor 2 : insulin/blood pressure).

    These two factors explained 54.6% of the total variance in the entire sample.

    The factor loading patterns were very similar in all race and age groups, based on high values of coefficients of congruence (0.89-1.0). (...)

    Mots-clés Pascal : Appareil circulatoire pathologie, Résistance, Insuline, Syndrome, Hyperinsulinémie, Obésité, Dyslipémie, Phénotype, Epidémiologie, Facteur risque, Physiopathologie, Adolescent, Homme, Adulte jeune, Enfant, Louisiane, Etats Unis, Amérique du Nord, Amérique, Lipide, Trouble métabolisme, Trouble nutrition, Métabolisme pathologie

    Mots-clés Pascal anglais : Cardiovascular disease, Resistance, Insulin, Syndrome, Hyperinsulinemia, Obesity, Dyslipemia, Phenotype, Epidemiology, Risk factor, Pathophysiology, Adolescent, Human, Young adult, Child, Louisiana, United States, North America, America, Lipids, Metabolic disorder, Nutrition disorder, Metabolic diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0504982

    Code Inist : 002B22E05. Création : 22/03/2000.