To determine if dietary long-chain polyunsaturated fatty acids (LCPUFA) affect the growth of formula-fed infants relative to breastfed infants.
A randomized, double-blind trial of three formula-fed groups and a parallel reference group of breastfed infants was conducted.
The three treatments were a placebo (no LCPUFA), docosahexaenoic acid (DHA) supplemented, and DHA plus arachidonic acid supplemented formulas fed for 12 months.
Infant weight, length, head circumference, and fatty acid status were assessed at 6,16,34 weeks, and 1 year of age.
Anthropometrics were repeated at 2 years of age.
There were no differences between the randomized formula groups for weight, length, or head circumference even after adjustment for gender, gestational age, and the actual age at assessment.
Post hoc regressions demonstrated a small negative association between DHA status at 16 weeks of age and weight at 1 and 2 years.
Dietary LCPUFA do not influence growth of healthy term infants to a clinically significant degree.
Mots-clés Pascal : Allaitement, Acide gras polyinsaturé, Supplémentation, Régime alimentaire, Croissance, Prise poids, Poids corporel, Docosahexaénoïque acide, Arachidonique acide, Effet biologique, Nourrisson, Homme, Etude comparative, Alimentation
Mots-clés Pascal anglais : Breast feeding, Polyunsaturated fatty acid, Supplementation, Diet, Growth, Weight gain, Body weight, Docosahexaenoic acid, Arachidonic acid, Biological effect, Infant, Human, Comparative study, Feeding
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0496072
Code Inist : 002B30A02A. Création : 22/03/2000.