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  1. Predicting deterioration in previously healthy infants hospitalized with respiratory syncytial virus infection.

    Article - En anglais


    To estimate the incidence of clinical deterioration leading to intensive care unit transfer in previously healthy infants with respiratory syncytial virus (RSV) infection hospitalized on a general pediatric unit and, to assess the hypothesis that history, physical examination, oximetry, and chest radiographic findings at time of presentation can accurately identify these infants.

    Study Design

    A virology database was used to identify and determine the disposition of all children <=1 year of age admitted to the Children's Hospital at Strong (CHaS) with RSV infection during the 1985 to 1994 respiratory seasons.

    Index patients were all previously healthy, full-term infants admitted initially to the general inpatient services at CHaS or Rochester General Hospital, a second University of Rochester teaching hospital, whose clinical deterioration led to transfer to the pediatric intensive care unit (PICU).

    These infants were matched retrospectively (for year and date of infection, sex, chronologic age, and race) with two hospitalized controls who did not require PICU transfer.

    Chest radiographic findings, respiratory rate (RR), O2 saturation, and presence of wheezing at time of presentation to the emergency department (ED) were compared.


    During the study years, 542 previously healthy, full-term infants were admitted to the general pediatric unit at CHaS with proven RSV infection.

    Ten (1.8% ; 95% confidence interval, 0.9%, 3. (...)

    Mots-clés Pascal : Hospitalisation, Virose, Infection, Appareil respiratoire pathologie, Virus syncytial humain, Spumavirinae, Retroviridae, Virus, Diagnostic, Prédiction, Complication, Indice gravité, Pronostic, Radiographie, Poumon, Oxymétrie, Epidémiologie, Incidence, Facteur risque, Nourrisson, Homme, Radiodiagnostic

    Mots-clés Pascal anglais : Hospitalization, Viral disease, Infection, Respiratory disease, Human syncytial virus, Spumavirinae, Retroviridae, Virus, Diagnosis, Prediction, Complication, Severity score, Prognosis, Radiography, Lung, Oxymetry, Epidemiology, Incidence, Risk factor, Infant, Human, Radiodiagnosis

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0494729

    Code Inist : 002B05C02C. Création : 22/03/2000.