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  1. Occupational physical activity and renal cell cancer : A nationwide cohort study in Sweden.

    Article - En anglais

    The causes of renal cell cancer remain incompletely understood.

    In one previous retrospective case-control study, high occupational physical activity has been associated with a decreased risk among men, but not among women.

    Our aim was to investigate the association between occupational physical activity and renal cell cancer in a large cohort in Sweden.

    A cohort of Swedish men and women was identified in the nationwide censuses in 1960 and 1970, and the reported occupations were classified into 4 levels of physical demands.

    Follow-up from 1971 through 1989 was accomplished through record linkages to the Swedish Cancer Registry.

    Multivariate Poisson regression models were used to estimate relative risk (RR) and 95% confidence intervals (CI).

    We found a monotonic increase in risk of renal cell cancer with decreasing level of occupational physical activity among men (p for trend<0.001).

    After adjustment for socio-economic status, place of residence, and calendar year of follow-up, men with long-term sedentary jobs had a 25% (RR=1.25,95% CI 1.02-1.53) increased risk compared to men with physically demanding occupations.

    Among women there was no association, the dose-risk trend was not significant (p for trend>0.50).

    Occupational physical activity was inversely associated with renal cell cancer among men. (...)

    Mots-clés Pascal : Hypernéphrome, Rein, Exercice physique, Facteur risque, Epidémiologie, Etude cohorte, Suède, Europe, Homme, Carcinome, Appareil urinaire pathologie, Rein pathologie, Tumeur maligne

    Mots-clés Pascal anglais : Grawitz tumor, Kidney, Physical exercise, Risk factor, Epidemiology, Cohort study, Sweden, Europe, Human, Carcinoma, Urinary system disease, Kidney disease, Malignant tumor

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0490539

    Code Inist : 002B14D01. Création : 22/03/2000.