The age-adjusted mortality rates of colorectal cancer have been rising in Taiwan over the past 2 decades, and colorectal cancer is now the third leading cause of cancer mortality in the country.
We conducted a hospital-based case-control study to clarify the nature of the association between physical activity, water intake and colorectal-cancer risk in Taiwan.
A total of 163 subjects (aged 33-80 years) with histologically confirmed primary colorectal cancer and 163 hospital controls were enrolled during 1992.
Dietary intake, physical activity and other lifestyle activities were assessed using a comprehensive food-frequency and lifestyle-activity questionnaire.
Adjusted odds ratios (OR) and 95% confidence intervals (Cl) were estimated using conditional logistic-regression analysis.
A strong inverse dose-response relation between increased water intake and rectal cancer was found among men after adjustment for other risk factors (p for trend=0.0005).
The OR for rectal cancer among men in the highest tertile of water intake was 0.08 (95% Cl, 0.02-0.35) compared with that among men in the lowest tertile (OR=I).
Similar but not significant trends were seen among women (p=0.29).
The OR for colon cancer among men with active leisure-time physical activity was 0.19 (95% Cl, 0.05-0.77) times that among sedentary men (p for trend=0.03).
However, physical activity was not associated with colon-cancer risk among women (p=0.48). (...)
Mots-clés Pascal : Tumeur maligne, Côlon, Rectum, Facteur risque, Epidémiologie, Exercice physique, Mode de vie, Prise eau, Etude cas témoin, Taiwan, Asie, Homme, Appareil digestif pathologie, Intestin pathologie, Côlon pathologie, Rectum pathologie
Mots-clés Pascal anglais : Malignant tumor, Colon, Rectum, Risk factor, Epidemiology, Physical exercise, Life style, Water intake, Case control study, Taiwan, Asia, Human, Digestive diseases, Intestinal disease, Colonic disease, Rectal disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0487706
Code Inist : 002B13B01. Création : 22/03/2000.