Association between breast feeding and asthma in 6 year old children : findings of a prospective birth cohort study.
Objectives To investigate the association between the duration of exclusive breast feeding and the development of asthma related outcomes in children at age 6 years.
Design Prospective cohort study
Setting Western Australia.
Subjects 2187 children ascertained through antenatal clinics at the major tertiary obstetric hospital in Perth and followed to age 6 years.
Main outcome measures Unconditional logistic regression to model the association between duration of exclusive breast feeding and outcomes related to asthma or atopy at 6 years of age, allowing for several important confounders : sex, gestational age, smoking in the household, and early childcare.
Results After adjustment for confounders, the introduction of milk other than breast milk before 4 months of age was a significant risk factor for all asthma and atopy related outcomes in children aged 6 years :
asthma diagnosed by a doctor (odds ratio 1.25,95% confidence interval 1.02 to 1.52) ;
wheeze three or more times since 1 year of age (1.41,1.14 to 1.76) ;
wheeze in the past year (1.31,1.05 to 1.64) ;
sleep disturbance due to wheeze within the past year (1.42,1.07 to 1.89) ;
age when doctor diagnosed asthma (hazard ratio 1.22,1.03 to 1.43) ;
age at first wheeze (1.36,1.17 to 1.59) ;
and positive skin prick test reaction to at least one common aeroallergen (1.30,1.04 to 1.61). (...)
Mots-clés Pascal : Asthme, Atopie, Enfant, Homme, Age scolaire, Prévention, Durée, Allaitement, Questionnaire, Etude cohorte, Australie, Océanie, Epidémiologie, Evaluation, Recommandation, Promotion santé, Appareil respiratoire pathologie, Bronchopneumopathie obstructive
Mots-clés Pascal anglais : Asthma, Atopy, Child, Human, School age, Prevention, Duration, Breast feeding, Questionnaire, Cohort study, Australia, Oceania, Epidemiology, Evaluation, Recommendation, Health promotion, Respiratory disease, Obstructive pulmonary disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0483761
Code Inist : 002B11B. Création : 22/03/2000.