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  1. Association between breast feeding and asthma in 6 year old children : findings of a prospective birth cohort study.

    Article - En anglais

    Objectives To investigate the association between the duration of exclusive breast feeding and the development of asthma related outcomes in children at age 6 years.

    Design Prospective cohort study

    Setting Western Australia.

    Subjects 2187 children ascertained through antenatal clinics at the major tertiary obstetric hospital in Perth and followed to age 6 years.

    Main outcome measures Unconditional logistic regression to model the association between duration of exclusive breast feeding and outcomes related to asthma or atopy at 6 years of age, allowing for several important confounders : sex, gestational age, smoking in the household, and early childcare.

    Results After adjustment for confounders, the introduction of milk other than breast milk before 4 months of age was a significant risk factor for all asthma and atopy related outcomes in children aged 6 years :

    • asthma diagnosed by a doctor (odds ratio 1.25,95% confidence interval 1.02 to 1.52) ;

    • wheeze three or more times since 1 year of age (1.41,1.14 to 1.76) ;

    • wheeze in the past year (1.31,1.05 to 1.64) ;

    • sleep disturbance due to wheeze within the past year (1.42,1.07 to 1.89) ;

    • age when doctor diagnosed asthma (hazard ratio 1.22,1.03 to 1.43) ;

    • age at first wheeze (1.36,1.17 to 1.59) ;

    • and positive skin prick test reaction to at least one common aeroallergen (1.30,1.04 to 1.61). (...)

    Mots-clés Pascal : Asthme, Atopie, Enfant, Homme, Age scolaire, Prévention, Durée, Allaitement, Questionnaire, Etude cohorte, Australie, Océanie, Epidémiologie, Evaluation, Recommandation, Promotion santé, Appareil respiratoire pathologie, Bronchopneumopathie obstructive

    Mots-clés Pascal anglais : Asthma, Atopy, Child, Human, School age, Prevention, Duration, Breast feeding, Questionnaire, Cohort study, Australia, Oceania, Epidemiology, Evaluation, Recommendation, Health promotion, Respiratory disease, Obstructive pulmonary disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0483761

    Code Inist : 002B11B. Création : 22/03/2000.