Intrauterine foetal growth retardation (IUGR) implies increased risk of morbility and mortality of the newborn.
Aetiology of intrauterine retardation is probably multifactorial and may include maternal infection, malnutrition, placental dysfunction, hypertension, toxaemia, smoking, professional and environmental exposure.
The work concentrates on the lead, zinc and lysozyme levels in blood and placental tissues of 50 females in the IUGR group and 43 females from a control group.
Statistically significant differences in zinc and lead levels between the compared group were found.
The IUGR group had lower zinc and higher lead levels.
A significant negative correlation of zinc and lead levels was observed.
We found a statistically significant relationship between lead levels in placental tissues and the age of the pregnant females of the IUGR group higher lysozyme levels were found.
On the basis of the discussed results the authors recommend zinc supplementation during the pregnancy.
Mots-clés Pascal : Poids naissance faible, Nouveau né, Homme, Analyse biochimique, Placenta, Zinc, Elément trace, Plomb, Toxicologie, Recommandation, Supplémentation, Gestation, République tchèque, Europe, Epidémiologie, Gestation pathologie, Prématurité, Nouveau né pathologie
Mots-clés Pascal anglais : Low birth weight, Newborn, Human, Biochemical analysis, Placenta, Zinc, Trace element, Lead, Toxicology, Recommendation, Supplementation, Pregnancy, Czech Republic, Europe, Epidemiology, Pregnancy disorders, Prematurity, Newborn diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0482911
Code Inist : 002B20F02. Création : 22/03/2000.