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  1. Fulltext. Breast cancer and oral contraceptive use in Asian-American women.

    Article - En anglais


    Breast cancer incidence has historically been 4-7 times higher in the United States than in Asia.

    A previous study by the authors in Asian-American women demonstrated a substantial increase in breast cancer risk in women who migrated from Asia to the United States, with the risk almost doubling during the first decade after migration.

    Increased use of oral contraceptives soon after migration to the United States could possibly explain this rapid rise in risk.

    In a population-based case-control study of Chinese, Filipino, and Japanese-American women, aged 20-55 years, who lived in San Francisco-Oakland, California ; Los Angeles, California ; and Oahu, Hawaii during 1983-1987,597 cases (70% of those eligible) and 966 controls (75%) were interviewed.

    Controls were matched to cases on age, ethnicity, and area of residence.

    Oral contraceptive (OC) use increased with time since migration ; 15.0% of Asian-born women who had been in the West<8 years, 33.4% of Asian-born women who had been in the West >=8 years, and 49.6% of Asian women born in the West had ever used OCs.

    However, duration of OC use (adjusted for age, ethnicity, study area, years since migration, education, family history of breast cancer and age at first full-term birth) was not associated with increased risk of breast cancer.

    Moreover, neither OC use before age 25 years nor before first full-term birth was associated with increased risk. (...)

    Mots-clés Pascal : Tumeur maligne, Glande mammaire, Contraception, Voie orale, Epidémiologie, Facteur risque, Homme, Femelle, Etats Unis, Amérique du Nord, Amérique, Asiatique, Immigration, Glande mammaire pathologie

    Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Contraception, Oral administration, Epidemiology, Risk factor, Human, Female, United States, North America, America, Asiatic, Immigration, Mammary gland diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0482256

    Code Inist : 002B20E02. Création : 22/03/2000.