To assess prospectively the relation between body mass index, weight gain, repeated intentional weight losses, and the risk of self-reported hypertension, the authors studied 46,224 women who were participants in the Nurses Health Study II, who were free of hypertension in 1993, and who completed questions on intentional weight losses between 1989 and 1993.
Women who reported they had intentionally lost >=20 Ibs (9 kg) >=3 times were classified as severe weight cyclers.
Women who had intentionally lost >=10 Ibs (4.5 kg) >=3 times, but who did not meet the criteria for severe weight cycling, were classified as mild weight cyclers.
Between 1993 and 1995,1,107 incident cases of diagnosed hypertension were reported.
Body mass index and weight gain, but not weight cycler status, were independently associated with the development of hypertension.
For each 10 Ib (4.5 kg) gain in weight between 1989 and 1993, the risk of hypertension increased 20% (odds ratio (OR)=1.20,95% confidence interval (Cl) 1.15,1.24).
After adjustment for body mass index and weight gain, the risks associated with mild weight cycling (OR=1.15,95% Cl 1.00,1.33) and severe weight cycling (OR=1.13,95% Cl 0.79,1.61) were small and not significant.
Thus, the results of this study offer support for the current weight guidelines and provide further evidence of the health risks associated with excessive weight and weight gain. (...)
Mots-clés Pascal : Hypertension artérielle, Obésité, Prise poids, Perte poids, Poids corporel, Epidémiologie, Facteur risque, Homme, Femelle, Etats Unis, Amérique du Nord, Amérique, Etat nutritionnel, Appareil circulatoire pathologie, Trouble nutrition
Mots-clés Pascal anglais : Hypertension, Obesity, Weight gain, Weight loss, Body weight, Epidemiology, Risk factor, Human, Female, United States, North America, America, Nutritional status, Cardiovascular disease, Nutrition disorder
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0482040
Code Inist : 002B12B05B. Création : 22/03/2000.