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  1. Is age a risk factor for major pancreatic surgery ? An analysis of 300 resections.

    Article - En anglais


    The aim of this study was to analyze if age alone is a risk factor in major pancreatic surgery.


    From September 1,1985 to December 31,1997,806 patients underwent surgery for malignant and benign diseases of the pancreas in a prospective case control study performed at the Department of Surgery, Johannes Gutenberg University Hospital Mainz.

    In 228 patients (men 

    N=139 ; women :

    • N=139 ;

    • n=89 ;

    • mean age : 61 years ;

    • range : 23-83 years) we performed partial (n=178) or total (n=50) pancreaticoduodenectomy, which was combined with portal vein resection in 16 cases.

    Left pancreatic resection was carried out in 72 patients (men : n=40 ; women : n=32 ; mean age : 65 years ; range : 28-86 years).


    Surgical complications after pancreaticoduodenectomy occurred in 22.1% of patients <=70 years and in 30.2% of patients>70 years, however, less than half of them had severe complications ranging below 50%. General complications developed in 16.1% of patients <=70 years and in 27.9% of patients>70 years (p<0.001).

    The mortality rates 30 and 90 days after surgery were 3.2% (<=70 years) and 2.3% (>70 years), and 6.0% (<70 years) and 6.9% (>70 years), respectively.

    Regression analysis showed the following factors to exert an independent influence on mortality : Pre-operative serum bilirubin, the diameter of the pancreatic duct, intra-operative blood loss and the occurrence of surgical and nonsurgical complications. (...)

    Mots-clés Pascal : Duodénopancréatectomie, Facteur risque, Morbidité, Mortalité, Age, Expérience professionnelle, Prévention, Complication, Epidémiologie, Homme, Duodénum, Pancréas, Chirurgie, Appareil digestif pathologie, Pancréas pathologie

    Mots-clés Pascal anglais : Pancreatoduodenectomy, Risk factor, Morbidity, Mortality, Age, Professional experience, Prevention, Complication, Epidemiology, Human, Duodenum, Pancreas, Surgery, Digestive diseases, Pancreatic disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0481907

    Code Inist : 002B25G03. Création : 22/03/2000.