The aim of this study was to analyze if age alone is a risk factor in major pancreatic surgery.
From September 1,1985 to December 31,1997,806 patients underwent surgery for malignant and benign diseases of the pancreas in a prospective case control study performed at the Department of Surgery, Johannes Gutenberg University Hospital Mainz.
N=139 ; women :
mean age : 61 years ;
range : 23-83 years) we performed partial (n=178) or total (n=50) pancreaticoduodenectomy, which was combined with portal vein resection in 16 cases.
Left pancreatic resection was carried out in 72 patients (men : n=40 ; women : n=32 ; mean age : 65 years ; range : 28-86 years).
Surgical complications after pancreaticoduodenectomy occurred in 22.1% of patients <=70 years and in 30.2% of patients>70 years, however, less than half of them had severe complications ranging below 50%. General complications developed in 16.1% of patients <=70 years and in 27.9% of patients>70 years (p<0.001).
The mortality rates 30 and 90 days after surgery were 3.2% (<=70 years) and 2.3% (>70 years), and 6.0% (<70 years) and 6.9% (>70 years), respectively.
Regression analysis showed the following factors to exert an independent influence on mortality : Pre-operative serum bilirubin, the diameter of the pancreatic duct, intra-operative blood loss and the occurrence of surgical and nonsurgical complications. (...)
Mots-clés Pascal : Duodénopancréatectomie, Facteur risque, Morbidité, Mortalité, Age, Expérience professionnelle, Prévention, Complication, Epidémiologie, Homme, Duodénum, Pancréas, Chirurgie, Appareil digestif pathologie, Pancréas pathologie
Mots-clés Pascal anglais : Pancreatoduodenectomy, Risk factor, Morbidity, Mortality, Age, Professional experience, Prevention, Complication, Epidemiology, Human, Duodenum, Pancreas, Surgery, Digestive diseases, Pancreatic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0481907
Code Inist : 002B25G03. Création : 22/03/2000.