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  1. Acute liver failure ; clinical features and management : Acute liver failure.

    Article - En anglais

    Acute liver failure (ALF) is uncommon and may be associated with a high mortality rate.

    Its aetiology shows considerable geographical variation, with viral hepatitis the most common worldwide, whilst acetaminophen (paracetamol) induced hepatotoxicity forms the most common precipitant in many developed countries.

    Its management requires meticulous intensive care and the effective management of haemodynamic, septic and cerebral complications.

    The early identification of patients unlikely to survive without emergency liver transplantation is important to maximize the possibility of an available graft.

    Survival in those patients who undergo transplantation may be in excess of 75%.

    Mots-clés Pascal : Insuffisance hépatique, Aigu, Exploration clinique, Etiopathogénie, Classification par stade, Complication, Conduite à tenir, Article synthèse, Homme, Transplantation, Appareil digestif pathologie, Foie pathologie, Chirurgie

    Mots-clés Pascal anglais : Liver failure, Acute, Clinical investigation, Etiopathogenesis, Stage classification, Complication, Clinical management, Review, Human, Transplantation, Digestive diseases, Hepatic disease, Surgery

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0476666

    Code Inist : 002B13C03. Création : 22/03/2000.