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  1. Development of a health-related quality-of-life questionnaire for individuals with gastroesophageal reflux disease a validation study.

    Article - En anglais

    This study was conducted to test the psychometric properties of a newly developed health-related quality-of-life (HRQoL) questionnaire.

    A total of 172 symptomatic GERD patients completed a 57-item questionnaire (containing the SF-12 ; symptom frequency/bothersomeness ; problems related to activities, sleep, work disability ; overall HRQoL ; and treatment satisfaction) at baseline, week 1 [retest (N=25) ], and week 4 [follow-up (N=100) ]. Internal-consistency reliability was acceptable for most scales (range : 0.74-0.92).

    Test-retest reliability was acceptable for most scales (ICC : 0.74-0.85).

    Construct validity was demonstrated based on observed correlations.

    Known-groups validity was upheld, as patients who experienced more symptom days and patients who reported higher pain reported worse HRQoL than those with less symptoms or less severe pain.

    When categorized according to change in pain severity, Guyatt's statistic for the « improved » and « worse » groups demonstrated responsiveness, although many of the scales for the « stable » group were also responsive.

    In conclusion, the HRQoL questionnaire was found to be reliable, valid, and responsive.

    Mots-clés Pascal : Reflux gastrooesophagien, Questionnaire, Validation, Qualité vie, Etude longitudinale, Evaluation, Evolution démographique, Résultat, Chimiothérapie, Lansoprazole, Homme, Benzimidazole dérivé, Appareil digestif pathologie, Oesophage pathologie, Antiulcéreux, Antisécrétoire, Inhibiteur enzyme

    Mots-clés Pascal anglais : Gastroesophageal reflux, Questionnaire, Validation, Quality of life, Follow up study, Evaluation, Demographic evolution, Result, Chemotherapy, Lansoprazole, Human, Benzimidazole derivatives, Digestive diseases, Esophageal disease, Antiulcer agent, Antisecretory agent, Enzyme inhibitor

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0476259

    Code Inist : 002B13A03. Création : 22/03/2000.