To evaluate the possible association between occupational exposures (risk factors) and male bladder cancer in the Negev region (southern Israel) to enable preventive strategies to be applied.
A total of 92 male bladder cancer patients, diagnosed at a regional medical center between 1989 and 1993, were studied by interview and compared with 92 males without oncological disease after matching by age and country of origin.
A special questionnaire was developed to gather information on demography, life-time occupational history, smoking habits, coffee consumption, and health status.
Statistical analysis of the case-referent data was done using the SPSS-5 package for performance of the chi-square test, conditional logistic regression, and multiple classification analysis.
Significant associations were found between bladder cancer occurrence and (1) three different groups of occupational exposures [a - solvents (P=0.002, OR not computed due to the lack of exposed persons among referents), b - dusts (P=0.02 ; OR=4.67), and c - exposure to multiple chemicals (P<0.001, OR=6.25) ; (2) nephrolithiasis (P=0.02, OR=11.00) ; and (3) cigarette smoking (P=0.01, OR=1.87).
Certain types of occupational exposure, different from that to aromatic amines and dyes, may be considered as contributing factors in the epidemiology of bladder cancer. (...)
Mots-clés Pascal : Israël, Asie, Epidémiologie, Exposition professionnelle, Tumeur maligne, Vessie urinaire, Homme, Médecine travail, Mâle, Appareil urinaire pathologie, Voie urinaire pathologie, Vessie pathologie
Mots-clés Pascal anglais : Israel, Asia, Epidemiology, Occupational exposure, Malignant tumor, Urinary bladder, Human, Occupational medicine, Male, Urinary system disease, Urinary tract disease, Bladder disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0474871
Code Inist : 002B14D02. Création : 22/03/2000.