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  1. A retrospective study of Creutzfeldt-Jakob disease in Belgium.

    Article - En anglais

    Using data from Belgian neuropathological archives, completed with the results of a comprehensive study of available medical records, we found 100 patients who fulfilled diagnostic criteria for probable or definite Creutzfeldt-Jakob d1551isease (CJD).

    Mean age at death was 63 years.

    The median disease duration was 9 months.

    Progressive mental deterioration was present in all cases, whereas signs of cerebellar dysfunction and myoclonus were found in approximately 80% of the patients.

    In 50% of the population, the EEG revealed characteristic abnormalities.

    Ninety-six patients suffered from the sporadic type of CJD, while 4 suffered from a hereditary form.

    In our series, we could find no evidence for the new variant, neither for an iatrogenic cause.

    Mots-clés Pascal : Encéphalopathie spongiforme Creutzfeldt Jakob, Infection, Electroencéphalographie, Prion, Registre, Epidémiologie, Incidence, Homme, Belgique, Europe, Rétrospective, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Maladie dégénérative, Electrodiagnostic

    Mots-clés Pascal anglais : Creutzfeldt Jakob disease, Infection, Electroencephalography, Prion, Register, Epidemiology, Incidence, Human, Belgium, Europe, Retrospective, Nervous system diseases, Central nervous system disease, Cerebral disorder, Degenerative disease, Electrodiagnosis

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0467690

    Code Inist : 002B17G. Création : 22/03/2000.