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  1. Linear growth and skeletal maturation in subjects with treated celiac disease.

    Article - En anglais

    Background 

    The aim of this study was to report on the long-term growth and development in a group of treated patients with celiac disease.

    Methods 

    The study includes 26 patients (1 1 boys and 15 girls) with typical celiac disease who were younger than 2.5 at diagnosis and were followed by means of a growth longitudinal monitoring from the introduction of a gluten-free diet (mean age, 1.7 ± 0.5 years) until adulthood, over a median period of 15.3 years.

    Growth indicators used were : height, skeletal age, weight and BMI.

    Results 

    At the time of admission, the patients had a general tendency to short stature, underweight and retarded skeletal maturation.

    They did not catch up completely in height and skeletal age after a dietary treatment period of 3 years.

    Most of them were seen to be slightly below average height for age during childhood and adolescence with skeletal maturity retardation, even if a fairly large interindividual variation of height profiles was evident.

    Conclusions 

    Notwithstanding the early treatment, the careful follow-up, and the good adhesion to the dietary rules of the patients under study, slight negative effects of the disease on growth were not avoided.

    Mots-clés Pascal : Mucoviscidose, Association, Traitement, Age osseux, Etude longitudinale, Taille corporelle, Croissance, Evaluation, Enfant, Homme, Adolescent, Italie, Europe, Appareil respiratoire pathologie, Appareil digestif pathologie, Pancréas pathologie, Maladie héréditaire, Métabolisme pathologie, Système ostéoarticulaire pathologie, Métabolisme

    Mots-clés Pascal anglais : Cystic fibrosis, Association, Treatment, Bone age, Follow up study, Body size, Growth, Evaluation, Child, Human, Adolescent, Italy, Europe, Respiratory disease, Digestive diseases, Pancreatic disease, Genetic disease, Metabolic diseases, Diseases of the osteoarticular system, Metabolism

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0466421

    Code Inist : 002B24O06. Création : 22/03/2000.