A cohort study was conducted to evaluate he mortality pattern among female and male workers in a cigarette factory.
The study followed 972 female workers and 761 male workers with at least 6 months of cumulative employment from 1 January 1962 through 1 July 1996.
Among women, mortality from all causes of death [standardized mortality ratio (SMR)=0.9 ; 95% confidence interval (CI)=0.8-1.1] and mortality from all malignant neoplasms (SMR=1.1 ; Cl=0.9-1.3) were consistent with reference rates.
Male workers had a significantly reduced overall mortality (SMR=0.8 ; Cl=0.7-0.9), while mortality from all malignant neoplasms was as expected (SMR=0.9 ; CI=0.7-1.0).
Among female workers the frequencies of deaths from diseases of nervous system (SMR=2.0 ; CI=1.1-3.4) and from non-Hodgkin's lymphoma (NHL) (SMR 2.7 : CI=1.0-5.6) were elevated at a statistically significant level.
No association between duration of employment and diseases of nervous system was observed.
A higher risk for NHL, based on three deaths, was reported among female workers with 15 or more years of employment (SMR=8.1 ; Cl=2.2-21.0).
Although based on small numbers, the excess of NHL here reported suggests that potential exposure to foliar residues of pesticides should be thoroughly considered in tobacco manufacturing.
Mots-clés Pascal : Usine, Fabrication, Cigarette, Tabac, Exposition professionnelle, Médecine travail, Homme, Italie, Europe, Epidémiologie, Mortalité, Pesticide, Résidu, Etude cohorte, Lymphome non hodgkinien
Mots-clés Pascal anglais : Industrial plant, Manufacturing, Cigarette, Tobacco, Occupational exposure, Occupational medicine, Human, Italy, Europe, Epidemiology, Mortality, Pesticides, Residue, Cohort study, Non Hodgkin lymphoma
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0465003
Code Inist : 002B03F. Création : 22/03/2000.